Chronic kidney disease

N14_CHRONKIDNEYDIS

chronic kidney disease: Impairment of the renal function secondary to chronic kidney damage persisting for three or more months.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N18
Hospital discharge: ICD-9 585
Cause of death: ICD-10 N18
Cause of death: ICD-9 585
KELA reimbursements: KELA codes 138

3 out of 7 registries used, show all original rules.

9343

diagram downward connector

Check minimum number of events None

9343

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

9389

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

9073

diagram downward connector
N14_CHRONKIDNEYDIS

Control definitions

Control exclude N14_RENFAIL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N17-N19
Name in latin Insufficientia renalis chronica

Summary Statistics

Key figures

All Female Male
Number of individuals 9073 2975 6098
Unadjusted prevalence (%) 2.41 1.41 3.67
Mean age at first event (years) 67.22 65.10 68.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 9.93 [7.68, 12.85] 3.0e-68 2814
15 years 0.01 2.41 [1.86, 3.12] 3.4e-11 571
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_CHRONKIDNEYDIS – Chronic kidney disease
GWS hits: 2

Survival analyses between endpoints

Plot

before Chronic kidney disease
after Chronic kidney disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic kidney disease