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Migraine, single triptan purchase ok & required. ICD-code if available is included

DOID EFO MESH PheWeb

MIGRAINE_TRIPTAN

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

TRIPTAN1

40862

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

40862

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Remove individuals based on genotype QC

39387

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MIGRAINE_TRIPTAN

Control definitions

Control conditions not TRIPTAN1

Extra metadata

First used in FinnGen datafreeze DF3

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 39387 32959 6428
Unadjusted prevalence (%) 10.45 15.63 3.87
Mean age at first event (years) 37.33 36.72 40.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.94 [0.72, 1.23] 6.8e-1 589
15 years 0.00 0.75 [0.56, 1.01] 6.2e-2 256
5 years 0.00 1.02 [0.70, 1.49] 9.1e-1 76
1 year 0.00 1.45 [0.83, 2.52] 1.9e-1 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MIGRAINE_TRIPTAN – Migraine, single triptan purchase ok & required. ICD-code if available is included
GWS hits: 39

Survival analyses between endpoints

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Plot

before Migraine, single triptan purchase ok & required. ICD-code if available is included
after Migraine, single triptan purchase ok & required. ICD-code if available is included

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Migraine, single triptan purchase ok & required. ICD-code if available is included

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Endpoint not on priority list, no data to show.