≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Wegener granulomatosis

DOID EFO MESH SNOMED PheWeb

M13_WEGENER

Granulomatosis with Polyangiitis: A small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M31.3
Hospital discharge: ICD-9 4464
Hospital discharge: ICD-8 4462
Cause of death: ICD-10 M31.3
Cause of death: ICD-9 4464
Cause of death: ICD-8 4462

2 out of 7 registries used, show all original rules.

428

diagram downward connector

Check minimum number of events None

428

diagram downward connector

Include endpoints None

428

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

413

diagram downward connector
M13_WEGENER

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Granulomatosis Wegener

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 413 210 203
Unadjusted prevalence (%) 0.11 0.10 0.12
Mean age at first event (years) 53.56 52.18 54.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.64 [1.78, 7.44] 3.9e-4 52
15 years 0.01 1.75 [0.79, 3.84] 1.7e-1 23
5 years 0.00 2.45 [0.98, 6.11] 5.5e-2 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_WEGENER – Wegener granulomatosis
GWS hits: 2

Survival analyses between endpoints

↥

Plot

before Wegener granulomatosis
after Wegener granulomatosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Wegener granulomatosis

↥

Endpoint not on priority list, no data to show.