Reactive arthropathies

M13_REACTARTH

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M02, M03*
Hospital discharge: ICD-9 7111|7115|7118|713
Hospital discharge: ICD-8 71490
Cause of death: ICD-10 M02, M03*
Cause of death: ICD-9 7111|7115|7118|713
Cause of death: ICD-8 71490

2 out of 7 registries used, show all original rules.

2886

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Check minimum number of events None

2886

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Include endpoints None

2886

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Remove individuals based on genotype QC

2813

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M13_REACTARTH

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2813 1553 1260
Unadjusted prevalence (%) 0.75 0.74 0.76
Mean age at first event (years) 43.80 41.99 46.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.84 [0.28, 2.57] 7.7e-1 214
15 years 0.00 0.72 [0.28, 1.83] 4.9e-1 94
5 years 0.00 1.57 [0.71, 3.44] 2.6e-1 47
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_REACTARTH – Reactive arthropathies
GWS hits:

Survival analyses between endpoints

Plot

before Reactive arthropathies
after Reactive arthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies

Endpoint not on priority list, no data to show.