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Polymyalgia rheumatica

DOID EFO MESH SNOMED PheWeb

M13_POLYMYALGIA

polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M35.3
Hospital discharge: ICD-9 725
Hospital discharge: ICD-8 4463
Cause of death: ICD-10 M35.3
Cause of death: ICD-9 725
Cause of death: ICD-8 4463

2 out of 7 registries used, show all original rules.

3602

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Check minimum number of events None

3602

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Include endpoints None

3602

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Remove individuals based on genotype QC

3501

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M13_POLYMYALGIA

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M35
Name in latin Polymyalgia rheumatica

Summary Statistics

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Key figures

All Female Male
Number of individuals 3501 2020 1481
Unadjusted prevalence (%) 0.93 0.96 0.89
Mean age at first event (years) 69.65 68.93 70.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.79 [2.11, 3.68] 4.2e-13 644
15 years 0.01 1.12 [0.84, 1.51] 4.4e-1 231
5 years 0.00 2.85 [2.26, 3.59] 5.6e-19 243
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYMYALGIA – Polymyalgia rheumatica
GWS hits: 1

Survival analyses between endpoints

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Plot

before Polymyalgia rheumatica
after Polymyalgia rheumatica

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Drugs most likely to be purchased after Polymyalgia rheumatica

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Endpoint not on priority list, no data to show.