Polyarteritis nodosa and related conditions

M13_POLYARTERETAL

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M30
Cause of death: ICD-10 M30

2 out of 7 registries used, show all original rules.

359

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Check minimum number of events None

359

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Remove individuals based on genotype QC

373

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M13_POLYARTERETAL

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Polyarteritis nodosa et condiciones cognatae

Similar endpoints

List of similar endpoints to Polyarteritis nodosa and related conditions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 373 218 155
Unadjusted prevalence (%) 0.10 0.10 0.09
Mean age at first event (years) 49.53 48.21 51.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits:

Survival analyses between endpoints

Plot

before Polyarteritis nodosa and related conditions
after Polyarteritis nodosa and related conditions

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Drugs most likely to be purchased after Polyarteritis nodosa and related conditions

Endpoint not on priority list, no data to show.