Lethal midline granuloma

M13_MIDGRANULOMA

lethal midline granuloma: An aggressive, progressive, and destructive lesion affecting the nasal cavities, paranasal sinuses, and the palate. The vast majority of cases are malignant lymphoproliferations affecting the midline of the face in patients with nasal type extranodal NK/T-cell lymphoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M31.2
Hospital discharge: ICD-9 4463
Cause of death: ICD-10 M31.2
Cause of death: ICD-9 4463

2 out of 7 registries used, show all original rules.

18

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Check minimum number of events None

18

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Include endpoints None

18

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Remove individuals based on genotype QC

18

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M13_MIDGRANULOMA

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Granuloma lineae medialis letalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 18 10 8
Unadjusted prevalence (%) 0.00 0.00 0.00
Mean age at first event (years) 52.49 52.22 52.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MIDGRANULOMA – Lethal midline granuloma
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Lethal midline granuloma

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Endpoint not on priority list, no data to show.