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Hypersensitivity angiitis

DOID EFO MESH SNOMED PheWeb

M13_HYPERANG

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M31.0
Hospital discharge: ICD-9 4462A
Hospital discharge: ICD-8 4461
Cause of death: ICD-10 M31.0
Cause of death: ICD-9 4462A
Cause of death: ICD-8 4461

2 out of 7 registries used, show all original rules.

138

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Check minimum number of events None

138

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Include endpoints None

138

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Remove individuals based on genotype QC

135

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M13_HYPERANG

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Angi(i)tis hypersensitivitatis

Summary Statistics

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Key figures

All Female Male
Number of individuals 135 68 67
Unadjusted prevalence (%) 0.04 0.03 0.04
Mean age at first event (years) 55.10 54.75 55.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_HYPERANG – Hypersensitivity angiitis
GWS hits:

Survival analyses between endpoints

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Plot

before Hypersensitivity angiitis
after Hypersensitivity angiitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypersensitivity angiitis

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Endpoint not on priority list, no data to show.