Other articular cartilage disorders

DOID EFO MESH SNOMED PheWeb

M13_CARTILAGE

cartilage disease: Softening and degeneration of the CARTILAGE. Pathological processes involving the chondral tissue (CARTILAGE).

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M24.1

Hospital discharge: ICD-9 7180

Hospital discharge: ICD-8 7249

Cause of death: ICD-10 M24.1

Cause of death: ICD-9 7180

Cause of death: ICD-8 7249

2 out of 7 registries used, show all original rules.

737

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Check minimum number of events None

737

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Include endpoints None

737

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Remove individuals based on genotype QC

723

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M13_CARTILAGE

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M24

Name in latin Alia vitia cartilaginum articularium

NAME	M13_CARTILAGE
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M241
HD_ICD_9	7180
HD_ICD_8	7249
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M241
COD_ICD_9	7180
COD_ICD_8	7249
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other articular cartilage disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	723	356	367
Unadjusted prevalence (%)	0.19	0.17	0.22
Mean age at first event (years)	36.79	36.24	37.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.89 [0.53, 1.50]	6.7e-1	57
15 years	0.00	0.70 [0.42, 1.16]	1.7e-1	24
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_CARTILAGE – Other articular cartilage disorders
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other articular cartilage disorders
after Other articular cartilage disorders

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Table

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Drugs most likely to be purchased after Other articular cartilage disorders

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Endpoint not on priority list, no data to show.