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Gonarthrosis, primary, with knee surgery

MESH PheWeb

M13_ARTHROSIS_KNEE_PRIM_KNEESURG

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

M13_ARTHROSIS_KNEE_PRIM_ICD10

41174

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Check pre-conditions, main-only, mode, registry filters

Operations: NOMESCO codes ^NGB|^NGC

1 out of 7 registries used, show all original rules.

19595

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Check minimum number of events None

19595

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Include endpoints None

19595

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Remove individuals based on genotype QC

19126

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M13_ARTHROSIS_KNEE_PRIM_KNEESURG

Control definitions

Control conditions not M13_ARTHROSIS_KNEE_PRIM_ICD10

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 19126 11820 7306
Unadjusted prevalence (%) 5.07 5.61 4.39
Mean age at first event (years) 66.72 66.38 67.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.35 [1.12, 1.63] 1.9e-3 1666
15 years 0.01 1.09 [0.93, 1.28] 3.1e-1 1036
5 years 0.00 1.21 [1.04, 1.41] 1.4e-2 367
1 year 0.00 1.07 [0.80, 1.42] 6.4e-1 58

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROSIS_KNEE_PRIM_KNEESURG – Gonarthrosis, primary, with knee surgery
GWS hits: 37

Survival analyses between endpoints

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Plot

before Gonarthrosis, primary, with knee surgery
after Gonarthrosis, primary, with knee surgery

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gonarthrosis, primary, with knee surgery

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Endpoint not on priority list, no data to show.