Other and unspecified disorders of skin and subcutaneous tissue related to radiation

L12_SKINRADINAS

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L59.8, L59.9

Cause of death: ICD-10 L59.8, L59.9

2 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints None

Remove individuals based on genotype QC

L12_SKINRADINAS

Control definitions

Control exclude L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

NAME	L12_SKINRADINAS
CONTROL_EXCLUDE	L12_RADIATIONRELATEDSKIN
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L59[8-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L59[8-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Other and unspecified disorders of skin and subcutaneous tissue related to radiation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	26	20	6
Unadjusted prevalence (%)	0.01	0.01	0.00
Mean age at first event (years)	57.10	56.74	58.28

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_SKINRADINAS – Other and unspecified disorders of skin and subcutaneous tissue related to radiation
GWS hits:

Survival analyses between endpoints

↥

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Other and unspecified disorders of skin and subcutaneous tissue related to radiation

↥

Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3