Paracetamol of NSAID medication

RX_PARACETAMOL_NSAID

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N02BE01|N02BE51|M01A|M01B

1 out of 7 registries used, show all original rules.

326388

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Check minimum number of events

Min. number of events 3

326388

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Include endpoints None

326388

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Remove individuals based on genotype QC

314977

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RX_PARACETAMOL_NSAID

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 314977 183675 131302
Unadjusted prevalence (%) 83.53 87.13 78.97
Mean age at first event (years) 40.90 38.10 44.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.73 [0.67, 0.79] 9.1e-14 27415
15 years 0.01 0.49 [0.46, 0.53] 2.9e-87 12464
5 years 0.00 0.60 [0.56, 0.64] 1.5e-53 3153
1 year 0.00 0.67 [0.60, 0.76] 1.7e-10 592

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_PARACETAMOL_NSAID – Paracetamol of NSAID medication
GWS hits: 15

Survival analyses between endpoints

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Plot

before Paracetamol of NSAID medication
after Paracetamol of NSAID medication

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Drugs most likely to be purchased after Paracetamol of NSAID medication

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Endpoint not on priority list, no data to show.