Lichen sclerosus et atrophicus

L12_LICHENSCLERATROPH

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L90.0

Hospital discharge: ICD-9 7010

Hospital discharge: ICD-8 70101

Cause of death: ICD-10 L90.0

Cause of death: ICD-9 7010

Cause of death: ICD-8 70101

2 out of 7 registries used, show all original rules.

2510

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Check minimum number of events None

2510

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Include endpoints None

2510

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Remove individuals based on genotype QC

2445

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L12_LICHENSCLERATROPH

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L90

Name in latin Lichen sclerosus et atrophicus

NAME	L12_LICHENSCLERATROPH
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L900
HD_ICD_9	7010
HD_ICD_8	70101
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L900
COD_ICD_9	7010
COD_ICD_8	70101
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Lichen sclerosus et atrophicus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2445	2123	322
Unadjusted prevalence (%)	0.65	1.01	0.19
Mean age at first event (years)	60.32	61.71	51.21

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.42 [1.37, 4.29]	2.4e-3	84
15 years	0.01	1.64 [0.95, 2.84]	7.8e-2	47
5 years	0.00	1.62 [0.93, 2.82]	9.2e-2	19
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_LICHENSCLERATROPH – Lichen sclerosus et atrophicus
GWS hits:

Survival analyses between endpoints

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Plot

before Lichen sclerosus et atrophicus
after Lichen sclerosus et atrophicus

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Table

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Drugs most likely to be purchased after Lichen sclerosus et atrophicus

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Endpoint not on priority list, no data to show.