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Perforation of oesophagus

DOID EFO MESH SNOMED PheWeb

K11_PERFOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K22.3
Hospital discharge: ICD-9 5304
Hospital discharge: ICD-8 5304
Cause of death: ICD-10 K22.3
Cause of death: ICD-9 5304
Cause of death: ICD-8 5304

2 out of 7 registries used, show all original rules.

120

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Check minimum number of events None

120

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Include endpoints None

120

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Remove individuals based on genotype QC

114

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K11_PERFOES

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K22
Name in latin Perforatio oesophagi

Summary Statistics

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Key figures

All Female Male
Number of individuals 114 43 71
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 60.05 58.32 61.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PERFOES – Perforation of oesophagus
GWS hits:

Survival analyses between endpoints

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Plot

before Perforation of oesophagus
after Perforation of oesophagus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Perforation of oesophagus

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Endpoint not on priority list, no data to show.