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Other diseases of oesophagus

DOID EFO MESH SNOMED PheWeb

K11_OTHDISOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Hospital discharge: ICD-9 530[5-9]
Hospital discharge: ICD-8 5302|5309
Hospital discharge: excluded ICD-10 K22.7
Cause of death: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Cause of death: ICD-9 530[5-9]
Cause of death: ICD-8 5302|5309

2 out of 7 registries used, show all original rules.

3013

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Check minimum number of events None

3013

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Include endpoints None

3013

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Remove individuals based on genotype QC

2936

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K11_OTHDISOES

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2936 1291 1645
Unadjusted prevalence (%) 0.78 0.61 0.99
Mean age at first event (years) 54.75 53.11 56.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [1.03, 2.18] 3.5e-2 559
15 years 0.01 0.95 [0.72, 1.27] 7.5e-1 230
5 years 0.00 1.99 [1.55, 2.56] 7.4e-8 147
1 year 0.00 4.19 [3.03, 5.79] 5.2e-18 57

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_OTHDISOES – Other diseases of oesophagus
GWS hits:

Survival analyses between endpoints

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Plot

before Other diseases of oesophagus
after Other diseases of oesophagus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other diseases of oesophagus

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Endpoint not on priority list, no data to show.