Gastroduodenal ulcer

K11_GASTRODUOULC

gastric ulcer: An ulcerated lesion in the mucosal surface of the stomach. It may progress to involve the deeper layers of the gastric wall. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K25, K26, K27, K28
Cause of death: ICD-10 K25, K26, K27, K28

2 out of 7 registries used, show all original rules.

8286

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Check minimum number of events None

8286

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Include endpoints

9563

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Remove individuals based on genotype QC

9216

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K11_GASTRODUOULC

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9216 3539 5677
Unadjusted prevalence (%) 2.44 1.68 3.41
Mean age at first event (years) 61.54 59.90 62.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.74 [2.26, 3.31] 6.1e-25 2817
15 years 0.01 1.44 [1.24, 1.68] 3.2e-6 1032
5 years 0.00 3.37 [2.99, 3.80] 7.6e-89 795
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_GASTRODUOULC – Gastroduodenal ulcer
GWS hits: 4

Survival analyses between endpoints

Plot

before Gastroduodenal ulcer
after Gastroduodenal ulcer

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gastroduodenal ulcer

Endpoint not on priority list, no data to show.