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Functional dyspepsia

DOID EFO MESH PheWeb

K11_FUNCDYSP

dyspepsia: An uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach pain, bloating, heartburn, nausea, and vomiting. Causes include gastritis, gastric ulcer, gastroesophageal reflux disease, pancreatic disease, and gallbladder disease.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K30
Hospital discharge: ICD-9 5368A
Hospital discharge: ICD-8 5361
Cause of death: ICD-10 K30
Cause of death: ICD-9 5368A
Cause of death: ICD-8 5361

2 out of 7 registries used, show all original rules.

9227

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Check minimum number of events None

9227

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Include endpoints None

9227

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Remove individuals based on genotype QC

8875

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K11_FUNCDYSP

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K20-K31
Name in latin Dyspepsia

Summary Statistics

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Key figures

All Female Male
Number of individuals 8875 6064 2811
Unadjusted prevalence (%) 2.35 2.88 1.69
Mean age at first event (years) 53.95 52.26 57.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.82 [1.26, 2.65] 1.6e-3 612
15 years 0.01 1.15 [0.85, 1.55] 3.7e-1 274
5 years 0.00 2.33 [1.82, 2.98] 2.0e-11 175
1 year 0.00 5.43 [4.07, 7.24] 1.1e-30 79

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_FUNCDYSP – Functional dyspepsia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Functional dyspepsia
after Functional dyspepsia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Functional dyspepsia

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Endpoint not on priority list, no data to show.