Disorders of oesophagus in diseases classified elsewhere

K11_DISOESINOTH

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K23*
Cause of death: ICD-10 K23*

2 out of 7 registries used, show all original rules.

545

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Check minimum number of events None

545

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Include endpoints None

545

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Remove individuals based on genotype QC

523

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K11_DISOESINOTH

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 523 250 273
Unadjusted prevalence (%) 0.14 0.12 0.16
Mean age at first event (years) 63.60 61.18 65.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.76 [1.80, 7.84] 4.2e-4 130
15 years 0.01 0.98 [0.46, 2.10] 9.7e-1 30
5 years 0.00 4.30 [2.41, 7.68] 7.9e-7 40
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_DISOESINOTH – Disorders of oesophagus in diseases classified elsewhere
GWS hits:

Survival analyses between endpoints

Plot

before Disorders of oesophagus in diseases classified elsewhere
after Disorders of oesophagus in diseases classified elsewhere

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Drugs most likely to be purchased after Disorders of oesophagus in diseases classified elsewhere

Endpoint not on priority list, no data to show.