Chronic pancreatitis

K11_CHRONPANC

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K86.00, K86.01, K86.08, K86.1
Hospital discharge: ICD-9 5771
Hospital discharge: ICD-8 5771
Cause of death: ICD-10 K86.00, K86.01, K86.08, K86.1
Cause of death: ICD-9 5771
Cause of death: ICD-8 5771
KELA reimbursements: KELA codes 133

3 out of 7 registries used, show all original rules.

3399

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Check minimum number of events None

3399

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Include endpoints None

3399

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Remove individuals based on genotype QC

3320

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K11_CHRONPANC

Control definitions

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3320 1057 2263
Unadjusted prevalence (%) 0.88 0.50 1.36
Mean age at first event (years) 55.03 55.41 54.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.52 [3.86, 7.90] 8.3e-21 727
15 years 0.01 2.50 [1.82, 3.44] 1.9e-8 234
5 years 0.01 6.19 [4.68, 8.17] 8.6e-38 190
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_CHRONPANC – Chronic pancreatitis
GWS hits: 4

Survival analyses between endpoints

Plot

before Chronic pancreatitis
after Chronic pancreatitis

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Drugs most likely to be purchased after Chronic pancreatitis

Endpoint not on priority list, no data to show.