Alcohol-induced chronic pancreatitis

ALCOPANCCHRON

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K86.00, K86.01, K86.08
Hospital discharge: ICD-9 5771C|5771D
Cause of death: ICD-10 K86.00, K86.01, K86.08
Cause of death: ICD-9 5771C|5771D

2 out of 7 registries used, show all original rules.

1833

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Check minimum number of events None

1833

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Include endpoints None

1833

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Remove individuals based on genotype QC

1794

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ALCOPANCCHRON

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1794 396 1398
Unadjusted prevalence (%) 0.48 0.19 0.84
Mean age at first event (years) 50.68 49.25 51.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.34 [2.50, 7.53] 1.8e-7 340
15 years 0.02 3.35 [2.20, 5.09] 1.8e-8 153
5 years 0.01 4.76 [3.26, 6.93] 5.1e-16 60
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCOPANCCHRON – Alcohol-induced chronic pancreatitis
GWS hits: 4

Survival analyses between endpoints

Plot

before Alcohol-induced chronic pancreatitis
after Alcohol-induced chronic pancreatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol-induced chronic pancreatitis

Endpoint not on priority list, no data to show.