Chronic gastritis

K11_CHRONGASTR

atrophic gastritis: GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K29.3, K29.4, K29.5
Hospital discharge: ICD-9 5351|5354
Hospital discharge: ICD-8 53503
Cause of death: ICD-10 K29.3, K29.4, K29.5
Cause of death: ICD-9 5351|5354
Cause of death: ICD-8 53503

2 out of 7 registries used, show all original rules.

9959

diagram downward connector

Check minimum number of events None

9959

diagram downward connector

Include endpoints None

9959

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

9570

diagram downward connector
K11_CHRONGASTR

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9570 5323 4247
Unadjusted prevalence (%) 2.54 2.53 2.55
Mean age at first event (years) 60.56 58.44 63.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.98 [1.65, 2.38] 2.2e-13 1646
15 years 0.01 1.30 [1.11, 1.51] 1.1e-3 780
5 years 0.00 2.43 [2.11, 2.79] 2.7e-35 489
1 year 0.00 4.60 [3.81, 5.55] 1.0e-56 176

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_CHRONGASTR – Chronic gastritis
GWS hits: 2

Survival analyses between endpoints

Plot

before Chronic gastritis
after Chronic gastritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic gastritis

Endpoint not on priority list, no data to show.