Achalasia of cardia

DOID MESH PheWeb

K11_ACHAL

No definition available.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K22.0

Hospital discharge: ICD-9 5300

Hospital discharge: ICD-8 5300

Cause of death: ICD-10 K22.0

Cause of death: ICD-9 5300

Cause of death: ICD-8 5300

2 out of 7 registries used, show all original rules.

520

diagram downward connector

Check minimum number of events None

520

diagram downward connector

Include endpoints None

520

diagram downward connector

diagram downward connector

Remove individuals based on genotype QC

506

diagram downward connector

K11_ACHAL

Control definitions

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K22

Name in latin Achalasia cardiae

NAME	K11_ACHAL
CONTROL_EXCLUDE	K11_OESSTODUO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K220
HD_ICD_9	5300
HD_ICD_8	5300
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K220
COD_ICD_9	5300
COD_ICD_8	5300
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Achalasia of cardia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	506	258	248
Unadjusted prevalence (%)	0.13	0.12	0.15
Mean age at first event (years)	50.44	47.10	53.91

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.28 [0.42, 3.93]	6.7e-1	67
15 years	0.01	0.83 [0.32, 2.11]	6.9e-1	26
5 years	0.00	1.95 [0.82, 4.64]	1.3e-1	19
1 year	0.00	6.29 [2.63, 15.06]	3.6e-5	12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: K11_ACHAL – Achalasia of cardia
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Achalasia of cardia
after Achalasia of cardia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Achalasia of cardia

↥

Endpoint not on priority list, no data to show.