All pneumoniae

J10_PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

58174

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J10_PNEUMONIA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 58174 24136 34038
Unadjusted prevalence (%) 15.43 11.45 20.47
Mean age at first event (years) 56.93 52.10 60.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.37 [6.74, 8.06] <1e-100 17110
15 years 0.01 2.67 [2.43, 2.95] 5.7e-87 3551
5 years 0.01 7.23 [6.71, 7.80] <1e-100 4882
1 year 0.01 40.21 [36.62, 44.15] <1e-100 7921

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_PNEUMONIA – All pneumoniae
GWS hits: 4

Survival analyses between endpoints

Plot

before All pneumoniae
after All pneumoniae

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Drugs most likely to be purchased after All pneumoniae

Endpoint not on priority list, no data to show.