Suppurative and necrotic conditions of lower respiratory tract

DOID EFO MESH SNOMED PheWeb

J10_NECROTIC

pleural empyema: The presence of pus in the thoracic cavity, between the visceral and parietal pleura. [database_cross_reference: NCIT:P378]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J85-J86

Cause of death: ICD-10 J85-J86

2 out of 7 registries used, show all original rules.

1391

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Check minimum number of events None

1391

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Include endpoints

J10_LUNGNECROSIS

J10_ABSCLUNGPNEUMO

J10_ABSCMEDIASTINUM

1533

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Remove individuals based on genotype QC

1477

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J10_NECROTIC

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	J10_NECROTIC
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	J10_LUNGNECROSIS\|J10_ABSCLUNGPNEUMO\|J10_ABSCMEDIASTINUM\|J10_PYOTHORAX
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J8[5-6]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J8[5-6]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Suppurative and necrotic conditions of lower respiratory tract based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1477	388	1089
Unadjusted prevalence (%)	0.39	0.18	0.65
Mean age at first event (years)	59.93	54.51	61.86

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_NECROTIC – Suppurative and necrotic conditions of lower respiratory tract
GWS hits: 1

Survival analyses between endpoints

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Plot

before Suppurative and necrotic conditions of lower respiratory tract
after Suppurative and necrotic conditions of lower respiratory tract

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Table

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Drugs most likely to be purchased after Suppurative and necrotic conditions of lower respiratory tract

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Endpoint not on priority list, no data to show.