Other acute lower respiratory infections

J10_LOWERINF

bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J20-J22
Cause of death: ICD-10 J20-J22

2 out of 7 registries used, show all original rules.

18144

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Check minimum number of events None

18144

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Remove individuals based on genotype QC

20873

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J10_LOWERINF

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 20873 10088 10785
Unadjusted prevalence (%) 5.54 4.79 6.49
Mean age at first event (years) 48.77 47.07 50.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.23 [3.54, 5.07] 2.1e-55 4205
15 years 0.01 1.66 [1.43, 1.93] 5.0e-11 1233
5 years 0.01 4.58 [4.12, 5.09] <1e-100 1630
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_LOWERINF – Other acute lower respiratory infections
GWS hits: 2

Survival analyses between endpoints

Plot

before Other acute lower respiratory infections
after Other acute lower respiratory infections

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Drugs most likely to be purchased after Other acute lower respiratory infections

Endpoint not on priority list, no data to show.