COPD/asthma/ILD related infections

DOID EFO MESH SNOMED PheWeb

PULM_INFECTIONS

pasteurellosis: Infections with bacteria of the genus pasteurella.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints

PULM_PNEUMONIA_SEPSIS

ACUTE_RESPIRATORY_INFECTIONS

121496

Remove individuals based on genotype QC

117312

PULM_INFECTIONS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

NAME	PULM_INFECTIONS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	PULM_PNEUMONIA_SEPSIS\|ACUTE_RESPIRATORY_INFECTIONS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to COPD/asthma/ILD related infections based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

117312

54365

62947

Unadjusted prevalence (%)

31.11

25.79

37.86

Mean age at first event (years)

44.17

43.10

45.10

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.69 [5.25, 6.18]	<1e-100	19844
15 years	0.01	2.65 [2.43, 2.89]	<1e-100	5006
5 years	0.01	6.32 [5.90, 6.78]	<1e-100	5666
1 year	0.01	31.52 [28.69, 34.64]	<1e-100	7558

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PULM_INFECTIONS – COPD/asthma/ILD related infections
GWS hits: 5

Survival analyses between endpoints

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Plot

before COPD/asthma/ILD related infections
after COPD/asthma/ILD related infections

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after COPD/asthma/ILD related infections

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3

COPD/asthma/ILD related infections

Endpoint definition

All original rules

Similar endpoints

Summary Statistics

Key figures

Number of individuals

Unadjusted prevalence

Mean age at first event

Follow-up

Absolute risk

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Number of individuals (N)