Venous thromboembolism

DOID EFO MESH SNOMED PheWeb

I9_VTE

Phlebitis: Inflammation of a vein.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I26, I80, O87.1, O88.2

Hospital discharge: ICD-9 415|451|6713|6714|6732

Hospital discharge: ICD-8 450|451|671|6739

Hospital discharge: excluded ICD-10 I80.0#

Hospital discharge: excluded ICD-9 4510

Cause of death: ICD-10 I26, I80, O87.1, O88.2

Cause of death: ICD-9 415|451|6713|6714|6732

Cause of death: ICD-8 450|451|671|6739

Cause of death: excluded ICD-10 I80.0#

Cause of death: excluded ICD-9 4510

2 out of 7 registries used, show all original rules.

19973

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Check minimum number of events None

19973

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Include endpoints None

19973

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Remove individuals based on genotype QC

19372

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I9_VTE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

NAME	I9_VTE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I26\|I80\|O871\|O882
HD_ICD_9	415\|451\|6713\|6714\|6732
HD_ICD_8	450\|451\|671\|6739
HD_ICD_10_EXCL	I800
HD_ICD_9_EXCL	4510
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I26\|I80\|O871\|O882
COD_ICD_9	415\|451\|6713\|6714\|6732
COD_ICD_8	450\|451\|671\|6739
COD_ICD_10_EXCL	I800
COD_ICD_9_EXCL	4510
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Venous thromboembolism based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	19372	10289	9083
Unadjusted prevalence (%)	5.14	4.88	5.46
Mean age at first event (years)	58.63	56.30	61.27

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.17 [2.68, 3.76]	9.7e-41	4315
15 years	0.01	1.27 [1.11, 1.45]	7.0e-4	1173
5 years	0.00	3.43 [3.07, 3.83]	<1e-100	1096
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VTE – Venous thromboembolism
GWS hits: 41

Survival analyses between endpoints

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Plot

before Venous thromboembolism
after Venous thromboembolism

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Venous thromboembolism

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