Pulmonary embolism


pulmonary embolism: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I26
Hospital discharge: ICD-9 415
Hospital discharge: ICD-8 450
Cause of death: ICD-10 I26
Cause of death: ICD-9 415
Cause of death: ICD-8 450

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude I9_PULMHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I26-I28
Name in latin Embolia pulmonalis

Summary Statistics

Key figures

All Female Male
Number of individuals 9243 4652 4591
Unadjusted prevalence (%) 2.45 2.21 2.76
Mean age at first event (years) 63.15 61.39 64.94


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.14 [4.89, 7.71] 6.8e-55 2520
15 years 0.01 1.47 [1.18, 1.84] 5.8e-4 480
5 years 0.01 5.15 [4.42, 5.99] 1.3e-99 648
1 year 0.01 40.83 [35.81, 46.54] <1e-100 1265

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_PULMEMB – Pulmonary embolism
GWS hits: 17

Survival analyses between endpoints


before Pulmonary embolism
after Pulmonary embolism

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Drugs most likely to be purchased after Pulmonary embolism