Varicose veins

I9_VARICVE

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I83
Hospital discharge: ICD-9 454
Hospital discharge: ICD-8 454
Cause of death: ICD-10 I83
Cause of death: ICD-9 454
Cause of death: ICD-8 454

2 out of 7 registries used, show all original rules.

30328

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Check minimum number of events None

30328

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Include endpoints None

30328

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Remove individuals based on genotype QC

29539

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I9_VARICVE

Control definitions

Control exclude I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I80-I89
Name in latin Varices membrorum inferiorum

Summary Statistics

Key figures

All Female Male
Number of individuals 29539 21808 7731
Unadjusted prevalence (%) 7.83 10.35 4.65
Mean age at first event (years) 45.85 43.85 51.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [1.04, 1.31] 7.2e-3 3819
15 years 0.01 0.84 [0.76, 0.93] 5.9e-4 1577
5 years 0.00 1.12 [1.00, 1.25] 4.8e-2 546
1 year 0.00 2.14 [1.80, 2.55] 4.0e-18 188

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_VARICVE – Varicose veins
GWS hits: 137

Survival analyses between endpoints

Plot

before Varicose veins
after Varicose veins

loading spinner Loading survival analyses plot