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Subarachnoid haemmorrhage

DOID EFO MESH SNOMED PheWeb

I9_SAH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I60
Hospital discharge: ICD-9 430
Hospital discharge: ICD-8 430
Cause of death: ICD-10 I60
Cause of death: ICD-9 430
Cause of death: ICD-8 430

2 out of 7 registries used, show all original rules.

3378

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Check minimum number of events None

3378

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Include endpoints None

3378

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Remove individuals based on genotype QC

3289

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I9_SAH

Control definitions

Control exclude I9_STR_EXH, I9_TIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I60-I69
Name in latin Haemorrhagia subarachnoidalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 3289 1684 1605
Unadjusted prevalence (%) 0.87 0.80 0.97
Mean age at first event (years) 54.70 54.06 55.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.73 [1.80, 4.13] 2.0e-6 916
15 years 0.01 1.42 [1.03, 1.96] 3.1e-2 283
5 years 0.00 2.03 [1.51, 2.74] 3.1e-6 105
1 year 0.01 33.65 [26.46, 42.77] <1e-100 330

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_SAH – Subarachnoid haemmorrhage
GWS hits: 2

Survival analyses between endpoints

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Plot

before Subarachnoid haemmorrhage
after Subarachnoid haemmorrhage

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Subarachnoid haemmorrhage

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