Hypertension, portal

I9_HYPTENSPOR

portal hypertension: Increased blood pressure in the portal venous system. It is most commonly caused by cirrhosis. Other causes include portal vein thrombosis, Budd-Chiari syndrome, and right heart failure. Complications include ascites, esophageal varices, encephalopathy, and splenomegaly.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K76.6
Hospital discharge: ICD-9 5723A
Cause of death: ICD-10 K76.6
Cause of death: ICD-9 5723A

2 out of 7 registries used, show all original rules.

77

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Check minimum number of events None

77

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Include endpoints None

77

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Remove individuals based on genotype QC

74

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I9_HYPTENSPOR

Control definitions

Control exclude CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K76
Name in latin Hypertensio venae portae

Summary Statistics

Key figures

All Female Male
Number of individuals 74 31 43
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 54.11 52.60 55.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HYPTENSPOR – Hypertension, portal
GWS hits:

Survival analyses between endpoints

Plot

before Hypertension, portal
after Hypertension, portal

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertension, portal

Endpoint not on priority list, no data to show.