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Hypertension, portal

DOID EFO MESH SNOMED PheWeb

I9_HYPTENSPOR

portal hypertension: Increased blood pressure in the portal venous system. It is most commonly caused by cirrhosis. Other causes include portal vein thrombosis, Budd-Chiari syndrome, and right heart failure. Complications include ascites, esophageal varices, encephalopathy, and splenomegaly.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K76.6
Hospital discharge: ICD-9 5723A
Cause of death: ICD-10 K76.6
Cause of death: ICD-9 5723A

2 out of 7 registries used, show all original rules.

77

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Check minimum number of events None

77

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Include endpoints None

77

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Remove individuals based on genotype QC

74

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I9_HYPTENSPOR

Control definitions

Control exclude CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K76
Name in latin Hypertensio venae portae

Summary Statistics

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Key figures

All Female Male
Number of individuals 74 31 43
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 54.11 52.60 55.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_HYPTENSPOR – Hypertension, portal
GWS hits:

Survival analyses between endpoints

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Plot

before Hypertension, portal
after Hypertension, portal

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertension, portal

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Endpoint not on priority list, no data to show.