Separation of retinal layers (serosa)

H7_RETINASEPAR

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H35.7
Cause of death: ICD-10 H35.7

2 out of 7 registries used, show all original rules.

1104

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Check minimum number of events None

1104

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Include endpoints None

1104

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Remove individuals based on genotype QC

1068

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H7_RETINASEPAR

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H35
Name in latin Separatio stratorum retinae

Summary Statistics

Key figures

All Female Male
Number of individuals 1068 401 667
Unadjusted prevalence (%) 0.28 0.19 0.40
Mean age at first event (years) 53.86 55.05 53.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.31 [0.57, 3.02] 5.2e-1 48
15 years 0.01 1.04 [0.42, 2.53] 9.4e-1 35
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_RETINASEPAR – Separation of retinal layers (serosa)
GWS hits:

Survival analyses between endpoints

Plot

before Separation of retinal layers (serosa)
after Separation of retinal layers (serosa)

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Drugs most likely to be purchased after Separation of retinal layers (serosa)

Endpoint not on priority list, no data to show.