Retinal haemorrhage

DOID EFO MESH SNOMED PheWeb

H7_RETINAHAEMORR

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H35.6

Hospital discharge: ICD-9 3628A

Hospital discharge: ICD-8 37701

Cause of death: ICD-10 H35.6

Cause of death: ICD-9 3628A

Cause of death: ICD-8 37701

2 out of 7 registries used, show all original rules.

590

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Check minimum number of events None

590

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Include endpoints None

590

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Remove individuals based on genotype QC

569

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H7_RETINAHAEMORR

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H35

Name in latin Haemorrhagia retinae

NAME	H7_RETINAHAEMORR
CONTROL_EXCLUDE	H7_CHOROIDRETINA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H356
HD_ICD_9	3628A
HD_ICD_8	37701
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H356
COD_ICD_9	3628A
COD_ICD_8	37701
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Retinal haemorrhage based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	569	293	276
Unadjusted prevalence (%)	0.15	0.14	0.17
Mean age at first event (years)	63.93	63.39	64.50

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.90 [1.50, 5.58]	1.5e-3	90
15 years	0.01	1.59 [0.87, 2.91]	1.3e-1	35
5 years	0.00	3.14 [1.64, 5.98]	5.3e-4	29
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINAHAEMORR – Retinal haemorrhage
GWS hits:

Survival analyses between endpoints

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Plot

before Retinal haemorrhage
after Retinal haemorrhage

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Table

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Drugs most likely to be purchased after Retinal haemorrhage

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Endpoint not on priority list, no data to show.