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Paralytic strabismus

DOID EFO MESH SNOMED PheWeb

H7_PARASTRAB

paralytic strabismus: An ocular deviation caused by a palsy to one or more of the extraocular muscles or nerves supplying them. [database_cross_reference: ORCID:0000-0003-0986-4123][database_cross_reference: ORCID:0000-0003-0986-4123]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H49
Cause of death: ICD-10 H49

2 out of 7 registries used, show all original rules.

1865

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Check minimum number of events None

1865

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Include endpoints

1975

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Remove individuals based on genotype QC

1905

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H7_PARASTRAB

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H49-H52
Name in latin Strabismus paralyticus

Similar endpoints

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List of similar endpoints to Paralytic strabismus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1905 951 954
Unadjusted prevalence (%) 0.51 0.45 0.57
Mean age at first event (years) 57.54 55.23 59.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.95 [1.96, 4.45] 2.4e-7 273
15 years 0.01 1.55 [0.98, 2.43] 6.0e-2 124
5 years 0.00 2.89 [1.97, 4.24] 5.1e-8 70
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_PARASTRAB – Paralytic strabismus
GWS hits:

Survival analyses between endpoints

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Plot

before Paralytic strabismus
after Paralytic strabismus

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Drugs most likely to be purchased after Paralytic strabismus

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Endpoint not on priority list, no data to show.