Keratitis

DOID EFO MESH SNOMED PheWeb

H7_KERATITIS

keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H16, H17, H18, H19*

Cause of death: ICD-10 H16, H17, H18, H19*

2 out of 7 registries used, show all original rules.

11741

Check minimum number of events None

11741

Include endpoints

H7_CORNULCER

H7_KERATITISOTH

H7_CORNEALSCAR

H7_HERPESKERATITIS

H7_KERATITISINOTH

12042

Remove individuals based on genotype QC

11611

H7_KERATITIS

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	H7_KERATITIS
CONTROL_EXCLUDE	H7_SCLERACORNEA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_CORNULCER\|H7_KERATITISOTH\|H7_CORNEALSCAR\|H7_HERPESKERATITIS\|H7_KERATITISINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H1[6-9]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H1[6-9]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Keratitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11611	6426	5185
Unadjusted prevalence (%)	3.08	3.05	3.12
Mean age at first event (years)	50.68	49.75	51.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.79 [1.27, 2.53]	8.4e-4	840
15 years	0.01	1.14 [0.81, 1.59]	4.6e-1	382
5 years	0.00	2.37 [1.83, 3.07]	6.9e-11	254
1 year	0.00	4.20 [3.12, 5.67]	4.7e-21	87

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 8

Survival analyses between endpoints

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Plot

before Keratitis
after Keratitis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Keratitis

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3