Other disorders of eye and adnexa

H7_EYEOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H55-H59
Cause of death: ICD-10 H55-H59

2 out of 7 registries used, show all original rules.

3974

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Check minimum number of events None

3974

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Remove individuals based on genotype QC

4023

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H7_EYEOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Other disorders of eye and adnexa based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 4023 2751 1272
Unadjusted prevalence (%) 1.07 1.30 0.76
Mean age at first event (years) 48.92 48.24 50.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.08 [1.36, 3.17] 6.9e-4 251
15 years 0.01 1.20 [0.85, 1.70] 3.1e-1 107
5 years 0.00 2.48 [1.80, 3.43] 3.6e-8 75
1 year 0.00 3.33 [1.99, 5.58] 4.7e-6 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_EYEOTH – Other disorders of eye and adnexa
GWS hits: 1

Survival analyses between endpoints

Plot

before Other disorders of eye and adnexa
after Other disorders of eye and adnexa

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Drugs most likely to be purchased after Other disorders of eye and adnexa

Endpoint not on priority list, no data to show.