Other specified and unspecified disorders of eye and adnexa

H7_EYEADNEXOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H57.8, H57.9
Hospital discharge: ICD-9 379[8-9]
Hospital discharge: ICD-8 37898
Cause of death: ICD-10 H57.8, H57.9
Cause of death: ICD-9 379[8-9]
Cause of death: ICD-8 37898

2 out of 7 registries used, show all original rules.

1114

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Check minimum number of events None

1114

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Include endpoints None

1114

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Remove individuals based on genotype QC

1074

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H7_EYEADNEXOTH

Control definitions

Control exclude H7_EYEOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1074 691 383
Unadjusted prevalence (%) 0.28 0.33 0.23
Mean age at first event (years) 46.76 46.08 47.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.55 [0.76, 3.17] 2.3e-1 149
15 years 0.01 1.18 [0.68, 2.05] 5.6e-1 71
5 years 0.00 1.93 [1.19, 3.14] 7.7e-3 33
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_EYEADNEXOTH – Other specified and unspecified disorders of eye and adnexa
GWS hits:

Survival analyses between endpoints

Plot

before Other specified and unspecified disorders of eye and adnexa
after Other specified and unspecified disorders of eye and adnexa

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Drugs most likely to be purchased after Other specified and unspecified disorders of eye and adnexa

Endpoint not on priority list, no data to show.