Extrapyramidal and movement disorders


basal ganglia disease: A disease involving the basal ganglia.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G20-G26
Cause of death: ICD-10 G20-G26

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 9833 4936 4897
Unadjusted prevalence (%) 2.61 2.34 2.95
Mean age at first event (years) 60.73 58.23 63.24


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.30 [2.55, 4.29] 2.0e-19 1761
15 years 0.01 2.03 [1.69, 2.44] 2.9e-14 859
5 years 0.00 3.11 [2.67, 3.61] 2.8e-49 575
1 year 0.00 4.40 [3.60, 5.36] 1.7e-48 166

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_XTRAPYR – Extrapyramidal and movement disorders
GWS hits: 3

Survival analyses between endpoints


before Extrapyramidal and movement disorders
after Extrapyramidal and movement disorders

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Drugs most likely to be purchased after Extrapyramidal and movement disorders

Endpoint not on priority list, no data to show.