info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Secondary parkinsonism+Parkinsonism in other disease

G6_PARKSCND

postencephalitic Parkinson disease: Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754)

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G21, G22*, G22*A52.1
Hospital discharge: ICD-9 3321
Hospital discharge: ICD-8 3420[8-9]
Cause of death: ICD-10 G21, G22*, G22*A52.1
Cause of death: ICD-9 3321
Cause of death: ICD-8 3420[8-9]

2 out of 7 registries used, show all original rules.

762

diagram downward connector

Check minimum number of events None

762

diagram downward connector

Include endpoints None

762

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

742

diagram downward connector
G6_PARKSCND

Control definitions

Control exclude G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 742 300 442
Unadjusted prevalence (%) 0.20 0.14 0.27
Mean age at first event (years) 61.81 61.23 62.21

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: G6_PARKSCND – Secondary parkinsonism+Parkinsonism in other disease
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Secondary parkinsonism+Parkinsonism in other disease

Endpoint not on priority list, no data to show.