≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Other and unspecified spinal muscular atrophies

DOID EFO MESH SNOMED PheWeb

G6_SPINAMUSCOTH

spinal muscular atrophy: Spinal muscular atrophy is a disorder of spinal motor neurons characterized clinically by the development of muscle weakness and atrophy.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G12.8, G12.9, G13*
Hospital discharge: ICD-9 335
Hospital discharge: ICD-8 34829|3489
Hospital discharge: excluded ICD-9 3350A|3351A|3352A
Cause of death: ICD-10 G12.8, G12.9, G13*
Cause of death: ICD-9 335
Cause of death: ICD-8 34829|3489

2 out of 7 registries used, show all original rules.

222

diagram downward connector

Check minimum number of events None

222

diagram downward connector

Include endpoints None

222

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

219

diagram downward connector
G6_SPINAMUSCOTH

Control definitions

Control exclude G6_NEUATR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 219 80 139
Unadjusted prevalence (%) 0.06 0.04 0.08
Mean age at first event (years) 56.45 48.87 60.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: G6_SPINAMUSCOTH – Other and unspecified spinal muscular atrophies
GWS hits: 8

Survival analyses between endpoints

↥

Plot

before Other and unspecified spinal muscular atrophies
after Other and unspecified spinal muscular atrophies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified spinal muscular atrophies

↥

Endpoint not on priority list, no data to show.