Migraine with aura


migraine with aura: A migraine disorder characterized by episodes that are preceded by focal neurological symptoms.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G43.1#
Hospital discharge: ICD-9 3460
Cause of death: ICD-10 G43.1#
Cause of death: ICD-9 3460

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 G43
Name in latin Hemicrania cum aura

Summary Statistics

Key figures

All Female Male
Number of individuals 7917 6569 1348
Unadjusted prevalence (%) 2.10 3.12 0.81
Mean age at first event (years) 43.09 42.43 46.34


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.92 [0.55, 1.55] 7.6e-1 122
15 years 0.00 0.76 [0.47, 1.21] 2.4e-1 65
5 years 0.00 1.37 [0.83, 2.24] 2.2e-1 28
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_MIGRAINE_WITH_AURA – Migraine with aura
GWS hits: 1

Survival analyses between endpoints


before Migraine with aura
after Migraine with aura

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Drugs most likely to be purchased after Migraine with aura