Migraine without aura

G6_MIGRAINE_NO_AURA

migraine without aura: A migraine disorder characterized by episodes that occur in the absence of preceding focal neurological symptoms.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G43.0#
Hospital discharge: ICD-9 3461
Cause of death: ICD-10 G43.0#
Cause of death: ICD-9 3461

2 out of 7 registries used, show all original rules.

6997

diagram downward connector

Check minimum number of events None

6997

diagram downward connector

Include endpoints None

6997

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

6730

diagram downward connector
G6_MIGRAINE_NO_AURA

Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 G43
Name in latin Hemicrania sine aura

Summary Statistics

Key figures

All Female Male
Number of individuals 6730 5742 988
Unadjusted prevalence (%) 1.78 2.72 0.59
Mean age at first event (years) 38.34 38.48 37.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.10 [0.59, 2.05] 7.7e-1 85
15 years 0.01 1.04 [0.61, 1.79] 8.8e-1 50
5 years 0.00 1.30 [0.68, 2.47] 4.3e-1 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MIGRAINE_NO_AURA – Migraine without aura
GWS hits: 4

Survival analyses between endpoints

Plot

before Migraine without aura
after Migraine without aura

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Migraine without aura