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Cerebral palsy and other paralytic syndromes

DOID EFO MESH SNOMED PheWeb

G6_CPETAL

cerebral palsy: A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G80-G83
Cause of death: ICD-10 G80-G83

2 out of 7 registries used, show all original rules.

3137

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Check minimum number of events None

3137

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Include endpoints

3637

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Remove individuals based on genotype QC

3497

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G6_CPETAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3497 1798 1699
Unadjusted prevalence (%) 0.93 0.85 1.02
Mean age at first event (years) 47.62 43.79 51.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.28 [3.28, 5.57] 5.6e-27 683
15 years 0.01 1.93 [1.47, 2.54] 2.3e-6 234
5 years 0.00 3.94 [3.00, 5.18] 1.1e-22 178
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_CPETAL – Cerebral palsy and other paralytic syndromes
GWS hits:

Survival analyses between endpoints

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Plot

before Cerebral palsy and other paralytic syndromes
after Cerebral palsy and other paralytic syndromes

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cerebral palsy and other paralytic syndromes

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Endpoint not on priority list, no data to show.