Focal epilepsy, strict definition

FE_STRICT

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not GE

391073

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

FE

6418

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Remove individuals based on genotype QC

6213

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FE_STRICT

Control definitions

Control exclude G6_EPLEPSY
Control conditions not GE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 6213 2976 3237
Unadjusted prevalence (%) 1.65 1.41 1.95
Mean age at first event (years) 50.31 46.59 53.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.68 [4.15, 7.77] 2.2e-27 1260
15 years 0.02 2.49 [1.98, 3.13] 7.0e-15 384
5 years 0.01 7.04 [5.95, 8.33] <1e-100 413
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FE_STRICT – Focal epilepsy, strict definition
GWS hits:

Survival analyses between endpoints

Plot

before Focal epilepsy, strict definition
after Focal epilepsy, strict definition

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Drugs most likely to be purchased after Focal epilepsy, strict definition

Endpoint not on priority list, no data to show.