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Acute and transient psychotic disorders

DOID EFO MESH SNOMED PheWeb

F5_PSYTRANS

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F23
Hospital discharge: ICD-9 298
Hospital discharge: ICD-8 298
Hospital discharge: excluded ICD-8 2989
Cause of death: ICD-10 F23
Cause of death: ICD-9 298
Cause of death: ICD-8 298
Cause of death: excluded ICD-8 2989

2 out of 7 registries used, show all original rules.

4454

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Check minimum number of events None

4454

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Include endpoints None

4454

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Remove individuals based on genotype QC

4255

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F5_PSYTRANS

Control definitions

Control exclude F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes psychoticae acutae et temporariae

Summary Statistics

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Key figures

All Female Male
Number of individuals 4255 2351 1904
Unadjusted prevalence (%) 1.13 1.12 1.15
Mean age at first event (years) 34.41 35.13 33.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.33 [1.58, 3.44] 2.0e-5 336
15 years 0.01 1.46 [1.04, 2.04] 2.8e-2 115
5 years 0.00 2.44 [1.73, 3.43] 3.7e-7 51
1 year 0.00 6.83 [4.43, 10.53] 3.3e-18 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PSYTRANS – Acute and transient psychotic disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Acute and transient psychotic disorders
after Acute and transient psychotic disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute and transient psychotic disorders

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Endpoint not on priority list, no data to show.