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Gender identity disorders

DOID EFO MESH SNOMED PheWeb

F5_GENDER

gender identity disorder: A disorder characterized by a strong and persistent cross-gender identification (such as stating a desire to be the other sex or frequently passing as the other sex) coupled with persistent discomfort with his or her sex (manifested in adults, for example, as a preoccupation with altering primary and secondary sex characteristics through hormonal manipulation or surgery).

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F64
Hospital discharge: ICD-9 3023|302[5-6]
Hospital discharge: ICD-8 3023
Cause of death: ICD-10 F64
Cause of death: ICD-9 3023|302[5-6]
Cause of death: ICD-8 3023

2 out of 7 registries used, show all original rules.

330

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Check minimum number of events None

330

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Include endpoints None

330

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Remove individuals based on genotype QC

318

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F5_GENDER

Control definitions

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F63-F69
Name in latin Perturbationes identitatis generis

Summary Statistics

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Key figures

All Female Male
Number of individuals 318 207 111
Unadjusted prevalence (%) 0.08 0.10 0.07
Mean age at first event (years) 29.20 26.57 34.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_GENDER – Gender identity disorders
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Gender identity disorders

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Endpoint not on priority list, no data to show.