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Psychotic depression

PheWeb

F5_DEPRESSION_PSYCHOTIC

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not (F5_SCHIZO
or F5_SCHIZOAFF
or F5_BIPO

373914

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: F32.3, F33.3
Hospital Discharge: ICD-10 F32.3, F33.3
Hospital discharge: ICD-9 2961E
Cause of death: ICD-10 F32.3, F33.3
Cause of death: ICD-9 2961E

3 out of 7 registries used, show all original rules.

2027

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Check minimum number of events None

2027

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Include endpoints None

2027

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Remove individuals based on genotype QC

1938

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F5_DEPRESSION_PSYCHOTIC

Control definitions

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF9

Summary Statistics

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Key figures

All Female Male
Number of individuals 1938 1231 707
Unadjusted prevalence (%) 0.51 0.58 0.43
Mean age at first event (years) 46.67 44.20 50.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.78 [1.93, 4.01] 4.0e-8 198
15 years 0.01 1.74 [1.24, 2.45] 1.4e-3 89
5 years 0.00 3.13 [2.22, 4.42] 8.8e-11 53
1 year 0.00 7.96 [5.07, 12.51] 2.3e-19 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_DEPRESSION_PSYCHOTIC – Psychotic depression
GWS hits:

Survival analyses between endpoints

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Plot

before Psychotic depression
after Psychotic depression

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psychotic depression

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Endpoint not on priority list, no data to show.