Unspecified dementia

F5_DEMNAS

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F03
Hospital discharge: ICD-9 290|2941
Hospital discharge: ICD-8 2900|29019
Cause of death: ICD-10 F03
Cause of death: ICD-9 290|2941
Cause of death: ICD-8 2900|29019

2 out of 7 registries used, show all original rules.

4155

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Check minimum number of events None

4155

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Include endpoints None

4155

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Remove individuals based on genotype QC

3994

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F5_DEMNAS

Control definitions

Control exclude F5_ORGANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 F00-F03
Name in latin Dementia non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 3994 1631 2363
Unadjusted prevalence (%) 1.06 0.77 1.42
Mean age at first event (years) 77.80 78.75 77.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 8.92 [7.88, 10.10] <1e-100 2713
15 years 0.02 2.28 [2.01, 2.60] 5.3e-36 632
5 years 0.01 5.93 [5.29, 6.65] <1e-100 1127
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_DEMNAS – Unspecified dementia
GWS hits: 3

Survival analyses between endpoints

Plot

before Unspecified dementia
after Unspecified dementia

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Drugs most likely to be purchased after Unspecified dementia

Endpoint not on priority list, no data to show.