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Acute alcohol intoxication

DOID EFO MESH SNOMED PheWeb

F5_ALCOHOLAC

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10.0
Hospital discharge: ICD-9 3050A
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.0
Cause of death: ICD-9 3050A
Cause of death: ICD-8 303

2 out of 7 registries used, show all original rules.

9212

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Check minimum number of events None

9212

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Include endpoints None

9212

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Remove individuals based on genotype QC

8957

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F5_ALCOHOLAC

Control definitions

Control exclude F5_SUBSTANCE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Similar endpoints

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List of similar endpoints to Acute alcohol intoxication based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 8957 2658 6299
Unadjusted prevalence (%) 2.38 1.26 3.79
Mean age at first event (years) 44.79 40.15 46.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.73 [2.82, 4.93] 3.2e-20 2160
15 years 0.01 2.02 [1.64, 2.50] 7.2e-11 714
5 years 0.00 3.88 [3.30, 4.56] 4.8e-61 417
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_ALCOHOLAC – Acute alcohol intoxication
GWS hits: 4

Survival analyses between endpoints

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Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

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Drugs most likely to be purchased after Acute alcohol intoxication

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Endpoint not on priority list, no data to show.