Acute alcohol intoxication

ALCOHOLACUTE10

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10.0
Cause of death: ICD-10 F10.0

2 out of 7 registries used, show all original rules.

6476

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Check minimum number of events None

6476

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Include endpoints None

6476

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Remove individuals based on genotype QC

6289

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ALCOHOLACUTE10

Control definitions

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Summary Statistics

Key figures

All Female Male
Number of individuals 6289 2232 4057
Unadjusted prevalence (%) 1.67 1.06 2.44
Mean age at first event (years) 49.12 42.62 52.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 16.21 [12.75, 20.61] <1e-100 1233
15 years 0.03 4.62 [3.62, 5.90] 7.2e-35 285
5 years 0.01 10.12 [8.21, 12.47] <1e-100 261
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits:

Survival analyses between endpoints

Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

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Drugs most likely to be purchased after Acute alcohol intoxication

Endpoint not on priority list, no data to show.